Coating Stoppers (Coating Closures)

The advantages of coating Stoppers (coating closures):
1. Coating Stoppers can prevent drugs etc. being absorbed on or spread into rubber closures; and avoid Halobutyl Rubber Stoppers being extracted by the drugs.
There will be interdiffusion effect between wrapped substances and bottle Stoppers: take medicines for example, medicines/drugs are usually been absorbed on the surface of and then spread into rubber Stoppers.
Although Halobutyl Rubber Stoppers have good chemical stability, it still will be extracted by medicines for the bottle closure's concentration gradient, which means the low molecular compounds in the bottle Stoppers will exude towards Stoppers surface. And the exudations will surely influence drug effect or pollute the drugs.
Coating Stoppers will be able to solve all above problems and to guarantee the drug effect.
2. No particle pollution caused by silicon oil.
Generally speaking, bottle Stoppers need siliconizing to prevent bonding between bottle closures and to reduce the produced particles during transportation; so as to guarantee rubber bottle Stoppers can be used normally on pharmacy making and filling machines and can be plug into bottles or vials etc. smoothly.
However, the particles in injection-use drugs, which derive from the silicon oil or silicon emulsion on rubber closures, are harmful for people's health. Coating rubber Stoppers, no need of siliconizing, is a good choice for medicine packaging. Coating bottle closures have smooth surface and can be used directly after sterilization.

Performance requirements for coating materials:
1. Extremely low gas permeability;
2. High moisture vapor transmission rate (MVTR);
3. Good resistance to chemical substances;
4. Good heat-ageing resistance;
5. High intrinsic cleanness;
6. Good ozone resistance and weatherability;
7. Stable radiation sterilization performance;
8. Nontoxic; odorless and no pollution.

Rubber discs for eurocpas ,Rubber discs 13mm for eurocpas ,Rubber discs 20 mm for eurocpas ,
Rubber discs 30 mm for eurocpas ,eurocaps with rubber discs,Eurocap for IV plastic bag

Applications of coating Stoppers (bottle closures):
Coating Halobutyl Rubber Stoppers are widely used in pharmaceutical packaging for cephalosporins, injectable pharmaceuticals and biological products etc.;

Note:
For the difference of coating materials, the closures' chemical substance resistance is also different; as a result, a suitable coating Stoppers should be chose based on drug properties.